This study investigates the influence of slope on the dynamics of erosional processes and the subsequent formation of soil profiles in the lowland loess hilly regions of Slovakia. Data from two localities were analyzed, confirming that slope has a significant impact on overall soil depth and the thickness of the humus horizon. The observed negative correlations between slope and soil depth (Báb: r=−0.206, p<0.05; Nová Vieska: r=−0.334, p<0.02) and between slope and humus horizon thickness (Báb: r=−0.227, p<0.01; Nová Vieska: r=−0.356, p<0.01) suggest that slope is a primary factor affecting pedogenesis in these landscapes. A critical slope value of 3° was found to significantly influence soil formation and characteristics. Steeper slopes are characterized by shallower soils and thinner humus horizons. These findings are crucial for effectively planning anti-erosional measures and for sustainable land management. This work contributes to a deeper understanding of soil formation processes in loess areas and the interactions between topographical factors and erosion.