A report on the environmental pollution health impact has been prepared for the PHARE Project EU/AIR/22 with the aim at the air prevention against the toxic and carcinogenic substances in the Slovak Republic. For the regions selected on the territory of Slovakia where the Project will be realized the publications concerning the changing health condition parameters of inhabitants have been reviewed. Since the sensitivity of the child s organism and its least immunity against polluted sebstances, comparative epidemiologic studies on selected children population have been carried out in the most number of publications. The analysis of published studies has revealed that the most frequent health changes have been recorded in the immune system (including allergy), the respiratory system and the growth development of children, respectively. The results of the epidemiological studies with the results of the laboratory research have been confronted. Obtained demographic data from the Institute of Health Information and Statistics concerning health state parameters of inhabitants residing in the selected regions have been comprised in reviewed summaries. Comparing the information obtained from the epidemiological studies with the demographic data it is evident that in the regions selected for PHARE Project the health state parameters of children population have been evaluated to be worse in comparison with the entire Slovak average.